gamma-Aminobutyric acid amide
4-aminobutyramide
CAS: 3251-08-9
Molecular Formula: C4H10N2O
gamma-Aminobutyric acid amide - Names and Identifiers
| Name | 4-aminobutyramide |
| Synonyms | Gaba amide Amide of Gaba 4-aminobutyramide γ-Aminobutyramide ButanaMide, 4-aMino- gamma-Aminobutyric acid amide Lenvatinib Mesilate Impurity 3 |
| CAS | 3251-08-9 |
| EINECS | 221-836-4 |
gamma-Aminobutyric acid amide - Physico-chemical Properties
| Molecular Formula | C4H10N2O |
| Molar Mass | 102.14 |
| Density | 1.0739 (rough estimate) |
| Boling Point | 191.46°C (rough estimate) |
| pKa | 16.48±0.40(Predicted) |
| Refractive Index | 1.4386 (estimate) |
gamma-Aminobutyric acid amide - Introduction
4-aminobutyramide (also known as succinamide) is an organic compound with the chemical formula C4H8N2O. The following is a brief description of the nature, use, formulation and safety information of 4-aminobutyramide:
Nature:
-Appearance: 4-aminobutyramide is a white crystalline solid.
-Solubility: It is soluble in water, alcohols and ketones solvents, insoluble in non-polar solvents.
-Melting point: The melting point of 4-aminobutyramide is about 155-157°C.
-Chemical properties: It is an electrophilic compound that can be used as an electrophile to react with many nucleophiles.
Use:
-Chemical synthesis: 4-aminobutyramide is a commonly used intermediate that can be used to prepare a variety of drugs and organic synthetic compounds.
-Dye: It can also be used as a raw material for certain dyes.
-Anthraquinone dye intermediate: It is one of the important compounds for preparing anthraquinone dye intermediates.
Preparation Method:
- 4-aminobutyramide is commonly prepared by the reaction of tetrachlorobutanamide (or brominated butanamide) with ammonia to remove chlorine (bromine) to generate the target product under alkaline conditions.
Safety Information:
- 4-aminobutyramide exposure may cause harm to human health. Inhalation, chewing, and contact with skin, eyes, and mucous membranes should be avoided during the procedure.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing when handling 4-aminobutyramide.
-When in contact with 4-aminobutyramide, rinse with water. If skin irritation or discomfort occurs, see a doctor in time.
-4-aminobutyramide should be stored in a dry, airtight container, away from ignition and oxidizing agents.
Nature:
-Appearance: 4-aminobutyramide is a white crystalline solid.
-Solubility: It is soluble in water, alcohols and ketones solvents, insoluble in non-polar solvents.
-Melting point: The melting point of 4-aminobutyramide is about 155-157°C.
-Chemical properties: It is an electrophilic compound that can be used as an electrophile to react with many nucleophiles.
Use:
-Chemical synthesis: 4-aminobutyramide is a commonly used intermediate that can be used to prepare a variety of drugs and organic synthetic compounds.
-Dye: It can also be used as a raw material for certain dyes.
-Anthraquinone dye intermediate: It is one of the important compounds for preparing anthraquinone dye intermediates.
Preparation Method:
- 4-aminobutyramide is commonly prepared by the reaction of tetrachlorobutanamide (or brominated butanamide) with ammonia to remove chlorine (bromine) to generate the target product under alkaline conditions.
Safety Information:
- 4-aminobutyramide exposure may cause harm to human health. Inhalation, chewing, and contact with skin, eyes, and mucous membranes should be avoided during the procedure.
-Wear appropriate personal protective equipment such as gloves, goggles and protective clothing when handling 4-aminobutyramide.
-When in contact with 4-aminobutyramide, rinse with water. If skin irritation or discomfort occurs, see a doctor in time.
-4-aminobutyramide should be stored in a dry, airtight container, away from ignition and oxidizing agents.
Last Update：2024-04-09 01:59:53
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